Table 1. MAGS prediction accuracy assigning 100% (A) or 85% (B) of the samples to the defined MAGS subtypes HSC, GMP, MEP, and an additional UC subtype.
A) | Predicted | Invalid Prediction (%) | ||||
Observed | HSC (%) | MEP (%) | GMP (%) | UC (%) | ||
HSC (N = 26) | 18 (69.2) | 4 (15.4) | 4 (15.4) | - | 8 (30.8) | |
MEP (N = 5) | 0 (0) | 5 (100) | 0 (0) | - | 0 (0) | |
GMP (N = 7) | 0 (0) | 0 (0) | 7 (100) | - | 0 (0) | |
B) | Predicted | Invalid Prediction (%) | ||||
Observed | HSC (%) | MEP (%) | GMP (%) | UC (%) | ||
HSC (N = 26) | 17 (65.4) | 3 (11.5) | 0 (0) | 6 (23.1) | 9 (34.6) | |
MEP (N = 5) | 0 (0) | 5 (100) | 0 (0) | 0 (0) | 0 (0) | |
GMP (N = 7) | 0 (0) | 0 (0) | 7 (100) | 0 (0) | 0 (0) |
The prediction accuracy was estimated in the validation-cohort (N = 38). Abbreviations: HSC, hematopoietic stem cells; GMP, granulocytic-monocytic progenitors; MEP, megakaryocyte-erythroid, UC, unclassified.