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. 2020 Apr 23;15(4):e0221985. doi: 10.1371/journal.pone.0221985

Table 4. Beta estimates and 95% confidence intervals for best fitting models* relative to their model-averaged parameter estimates.

PACC4 Executive Function
Model Term MA beta (CI) Best model beta (CI)* MA CI Best model beta (CI)*
APOE Risk -0.008 (-0.11–0.08) -0.007 (-1.06–0.09) -0.012 (-0.13–0.10) -1.41e-02 (-1.31e-01 - .10)
WRAT III Reading subtest 0.046 (0.04–0.05) 0.0457 (3.75e-02-0.05) 0.028 (0.02–0.04) 2.81e-02 (1.87e-02–0.04)
Age -0.042 (-0.05- -0.03) -0.042 (-5.08e-02 - -0.03) -0.053 (-0.06- -0.05) -5.21e-02 (-5.79e-02 - -0.05)
Sex -0.347 (-1.36–0.76) -0.401(-1.37e+00 - .52) -0.548 (-1.21–0.14) -5.64e-01 (-1.19e-02–0.04)
Age*Sex -0.008 (-0.26–0.01) -0.007 (9–2.22e-02 - .01) 0 (-0.01–0.01) -5.25e-05 (-9.91e-03–0.01)
Met Hours per Week (Physical Activity) -0.001 (-0.04–0.02) -- -0.001 (-0.02–0.01) --
MIND (Diet) 0.018 (-0.66–0.54) -- -0.252 (-1.04- -0.02) -3.55e-01 (-6.53e-01 - -0.03)
FCAS (Cognitive Activity) -0.306 (-0.92–0.25) -0.397 (9–8.48e-01–0.064) 0.056 (-0.19–0.79) 1.15e-01 (-1.95e-01–0.44)
Physical Activity*age 0 (0.0–0.0) -- 0 (0.0–0.0) --
MIND Diet*age 0 (-0.01–0.01) -- 0.004 (0.00–0.02) 5.18e-03 (7.28e-05–0.01)
Cognitive Activity*age 0.006 (-0.002–0.02) 0.007 (2.95e-05–0.01) 0 (-0.01–0.01) -2.17e-01 (-5.15–0.005)
Physical Activity*MIND Diet*age 0 (-0.001–0.00) -- 0 (-0.00–0.00) --
Physical Activitys*Cognitive Activity* age 0 (0.00–0.00) -- 0 (0.00–0.00) --
MIND Diet *Cognitive Activity*age 0 (-0.01–0.003) -- -0.001 (-0.01–0.00) -3.00e-03 (-7.72e-03-0.002)

*"Best Model" presented only if LRT with M1 showed the model added significantly above covariates. PACC-4 best model = Model 4; Executive Function best model = Model 8.

Abbreviations: PACC-4 = Preclinical Alzheimer’s Cognitive Composite Score-4; MA = Model-averaged; CI = 95% Confidence Interval; MIND = Mediterranean-DASH Intervention for Neurodegenerative Delay (Morris et al., 2015); FCAS = Florida Cognitive Activities Scale (Schinka et al., 2004)