Table 2. Peak pressures (kPa) per region (of interest) for each footwear condition.

	Shoe-A	Insole-A	Insole-B	Insole-C	Athletic shoe	Non-therapeutic shoe	P-value
Anatomical foot regions
MTH1	132 ± 41***	155 ± 52§¶	173 ± 76§	199 ± 79§%	227 ± 80***	281 ± 103***	< .001
MTH2-3	141 ± 34$¶	149 ± 31¶	171 ± 42§	197 ± 60§%	198 ± 40§%&	302 ± 75***	< .001
MTH4-5	117 ± 34	112 ± 26¶	119 ± 31¶	134 ± 42%$	133 ± 38§%&	161 ± 61***	< .001
Hallux	156 ± 41	167± 44	171 ± 41	175 ± 52	185 ± 56§	205 ± 73§¶	< .001
Midfoot	109 ± 30¶	120 ± 24¶	121 ± 34¶	143 ± 36***	94 ± 19%$¶	88 ± 20§%$¶	< .001
Hindfoot	190 ± 51	176 ± 40$	211 ± 49%¶	175 ± 38$	198 ± 40%¶&	269 ± 51***	< .001
Regions with barefoot peak pressure >450kPa (n)
MTH1 (n = 25)	140 ± 53***	173 ± 64§¶	201 ± 96§	212 ± 99§%	257 ± 102***	337 ± 127***	< .001
MTH2 (n = 21)	138 ± 41§¶	160 ± 39$¶	191 ± 49§%	223 ± 69§%	216 ± 46§%$&	350 ± 88***	< .001
MTH3 (n = 11)	159 [119–199]¶	154 [122–179]	166 [134–234]	190 [160–243]§	199 [193–221]	342 [273–403]	< .001
MTH4 (n = 5)	101 [86–132]	108 [82–116]	107 [90–121]	114 [90–144]	168 [138–197]%	208 [164–236]%$¶	.002
MTH5 (n = 14)	100 [88–132]	76 [62–99]	84 [78–98]	71 [50–93]	140 [115–169]***	187 [137–228]***	< .001
Hallux (n = 10)	159 [139–177]	191 [143–203]	186 [146–230]	176 [156–212]	190 [148–224]	228 [174–315]$	0.006

data are mean ± SD or median [IQR], with n = 24 for the analysis of anatomical foot regions and n as specified for the analysis of regions with a barefoot peak pressure >450 kPa.

*** significant difference vs. all other concepts (p < .05)

^§ significant difference vs. Shoe-A (p < .05)

^% significant difference vs. Insole-A (p < .05)

^$ significant difference vs. Insole-B (p < .05)

^¶ significant difference vs. Insole-C (p < .05)

^& significant difference between Athletic shoe and Non-therapeutic shoe (p < .05)