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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Jan 13;204(5):1201–1213. doi: 10.4049/jimmunol.1901205

Figure 6: Calcitriol induces IL-10 secretion by Th9 cells and promotes Foxp3 binding at Il9 gene.

Figure 6:

a) IL-10 and Foxp3 expression by Th9 cells treated with calcitriol is determined by q RT-PCR. b) The frequency of IL-10+ cells in the presence of calcitriol and anti-IL-10 (30 μg/mL) has been depicted in the representative FACS plots. The graphs represent the frequency of IL-9 and IL-10-positive cells in the presence of calcitriol and anti-IL-10 from 3 independent experiments. c) Foxp3 binding at three CNS of Il9 gene was determined by ChIP. Graphs depict mean± S.D of 3 independent experiments *p<0.05, **p<0.01 when compared to Th9 cells alone and #p<0.05, ##p<0.01 when compared to Th9 cells in the presence of calcitriol.