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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2019 Nov 13;33(3):446–457. doi: 10.1111/pcmr.12837

Figure 2. Expression of MX2 is associated with a better melanoma specific survival.

Figure 2.

a) Kaplan-Meier melanoma specific survival analysis of 703 primary melanomas and b) Kaplan-Meier overall survival analysis of 339 TCGA metastatic melanomas stratified by median MX2 RNA expression where low is defined as bellow median. Analysis performed applying univariate Cox proportional hazard model. c) MX2 RNA expression in High, Intermediate and Low Immune subgroups. d) Expression quantitative trait loci (eQTL) analysis of MX2 gene single nucleotide polymorphism rs45430 in 703 primary melanomas e) Representative immunohistochemistry staining of MX2 in 1) nevi, 2) primary and 3) and 4) metastatic melanoma.