Comparison 7. Sevelamer versus calcium‐containing phosphate binders.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 PTH	2	48	Mean Difference (IV, Random, 95% CI)	51.92 [‐77.53, 181.36]
2 ALP	2	48	Mean Difference (IV, Random, 95% CI)	90.48 [‐139.38, 320.35]
3 Calcium‐phosphorus product	2	48	Mean Difference (IV, Random, 95% CI)	‐1.12 [‐5.88, 3.64]
4 Calcium	2	48	Mean Difference (IV, Random, 95% CI)	‐0.40 [‐1.16, 0.36]
5 Phosphorus	2	48	Mean Difference (IV, Random, 95% CI)	0.17 [‐0.37, 0.71]
6 Bone histomorphometry	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
6.1 Bone formation rate [µm3/mm2/d]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.2 Fall in bone formation rate [%]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.3 Eroded perimeter [%]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.4 Osteoid area [%]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.5 Osteoid perimeter [%]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.6 Osteoid seam width [µm]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6.7 Bone area [%]	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]