Table 1.

Summary of recommended first-line ART regimens for children and adolescents.

	Children 3 to <10 year and adolescents <35 kg	Adolescents (10–19 year) ≥35 kg
Preferred	ABC + 3TC + EFV	TDF + 3TC (or FTC) + EFV
Alternatives	ABC + 3TC + NVP	AZT + 3TC + EFV
	AZT + 3TC + EFV	AZT + 3TC + NVP
	AZT + 3TC + NVP	TDF + 3TC (or FTC) + NVP
	TDF + 3TC (or FTC) + EFV
	TDF + 3TC (or FTC) + NVP
Special	d4T + 3TC + EFV	ABC + 3TC + EFV
circumstances	d4T + 3TC + NVP	ABC + 3TC + NVP

These recommendations apply to children and adolescents who initiate first-line ART as per WHO Clinical Guidelines.