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. 2020 Apr 23;58(5):e01785-19. doi: 10.1128/JCM.01785-19

TABLE 6.

ROC curve-predicted sensitivity at fixed specificitya

Test kit Fixed specificity
99%
98%
97%
96%
95%
90%
% P % P % P % P % P % P
BioPlex 2200 Lyme Total 91.1 Ref 91.1 Ref 91.1 Ref 92.2 Ref 92.2 Ref 95.6 Ref
Immunetics Lyme C6 82.2 0.008 83.3 0.016 86.7 0.125 86.7 0.063 86.7 0.063 88.9 0.031
Zeus Borrelia VlsE1/pepC10 76.7 <0.001 84.4 0.031 84.4 0.031 86.7 0.063 87.8 0.125 88.9 0.031
bioMérieux VIDAS Lyme polyvalent 47.8 <0.001 71.1 <0.001 74.4 <0.001 75.6 <0.001 75.6 <0.001 82.2 0.002
bioMérieux VIDAS Lyme II (lgM+IgG) 77.8 <0.001 77.8 <0.001 77.8 <0.001 80.0 0.001 80.0 0.001 83.3 0.001
bioMérieux VIDAS Lyme II lgM 50.0 <0.001 50.0 <0.001 52.2 <0.001 57.8 <0.001 58.9 <0.001 67.8 <0.001
bioMérieux VIDAS Lyme II lgG 77.8 <0.001 84.4 0.031 84.4 0.031 84.4 0.016 84.4 0.016 84.4 0.002
a

The ROC curves generated in Fig. 1 were used to measure the predicted sensitivity of the Lyme assays at the selected specificity levels shown. Ref, reference.