Table 3.
Effect of Myrica salicifolia on the Body Weights, Packed Cell Volume, and Temperature of Plasmodium berghei–Infected Mice in the 4-Day Suppressive Test.*
Group | Temperature (°C) | Weight (g) | Packed Cell Volume | ||||||
---|---|---|---|---|---|---|---|---|---|
D0 | D4 | % Change | D0 | D4 | % Change | D0 | D4 | % Change | |
NC | 36.5 ± 0.374 | 35.74 ± 0.28 | −2.12 | 27.3 ± 2.91 | 25.34 ± 2.99 | −7.73 | 52 ± 1.04 | 43.4 ± 2.16 | −19.82 |
100 mg/kg | 37.34 ± 0.373 | 36.94 ± 0.37 | −1.08b1 | 27.92 ± 0.59 | 26.8 ± 0.92 | −4.18 | 54 ± 0.70 | 49.6 ± 0.68 | −8.87 |
200 mg/kg | 37 ± 0.18 | 37 ± 0.30 | 0 | 25.7 ± 1.10 | 24.72 ± 1.04 | −3.96b2 | 51.4 ± 0.51 | 48.6 ± 0.51 | −5.76 |
400 mg/kg | 36.9 ± 0.31 | 37 ± 0.21a1 | 0.27 | 29.22 ± 2.22 | 28.54 ± 2.24 | −2.38 | 54.6 ± 1.50 | 53 ± 1.67 | −3.01 |
25 mg/kg CQ | 36.52 ± 0.30 | 37.32 ± 0.21a2 | 2.14a2 | 27.72 ± 4.21 | 28.8 ± 4.20 | 3.75a2 | 53.4 ± 2.69 | 54 ± 2.38 | 1.11 |
Abbreviations: CQ, chloroquine diphosphate; NC, normal control; D0, day infection was initiated; D4, fifth day of infection.
* Values are presented as mean ± SD (standard deviation). Statistical significance as compared with treatment control denoted by 1 P < .05, 2 P < .01, 3 P < .001, 4 P < .0001, acompared with NC, and bcompared with CQ.