Table 7.
Group | Temperature (°C) | Weight (g) | Packed Cell Volume | ||||||
---|---|---|---|---|---|---|---|---|---|
D0 | D4 | % Change | D0 | D4 | % Change | D0 | D4 | % Change | |
NC | 36.72 ± 0.28 | 35.66 ± 0.29 | 2.87 ± 0.96 | 31.58 ± 0.79 | 29.56 ± 0.74 | 6.38 ± 0.73 | 53.80 ± 1.07 | 45.20 ± 1.15 | 15.90 ± 2.29 |
100 mg/kg | 36.80 ± 0.25 | 35.70 ± 0.42 | 3.00 ± 0.48b2 | 30.10 ± 0.99 | 28.76 ± 0.93 | 4.44 ± 0.38b3 | 56.00 ± 0.45 | 50.40 ± 0.75a1,b1 | 10.02 ± 0.77a1,b3 |
200 mg/kg | 36.30 ± 0.44 | 35.88 ± 0.29 | −0.56 ± 0.64a2 | 31.84 ± 0.58 | 31.16 ± 0.39 | 2.08 ± 0.89a1,b1 | 54.00 ± 1.41 | 50.80 ± 1.93a1,b1 | 6.04 ± 1.26a3,b1 |
400 mg/kg | 37.10 ± 0.32 | 36.76 ± 0.33 | −0.27 ± 0.29a2 | 30.54 ± 0.50 | 30.38 ± 0.68 | 0.56 ± 0.71a2 | 56.00 ± 055 | 53.80 ± 0.49a3 | 2.85 ± 0.90a4 |
25 mg/kg CQ | 36.76 ± 0.19 | 36.86 ± 0.98 | −0.28 ± 0.33a2 | 29.96 ± 0.68 | 30.56 ± 0.91 | −1.96 ± 1.39a4 | 56.00 ± 1.14 | 56.94 ± 1.05a4 | −0.02 ± 0.56a4 |
Abbreviations: CQ, chloroquine diphosphate; NC, normal control; D0, day infection was initiated; D4, fifth day of infection.
* Values are presented as mean ± SEM (standard error of the mean). Statistical significance denoted by 1 P < .05, 2 P < .01, 3 P < .001, 4 P < .0001, acompared with NC, and bcompared with CQ.