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. 2020 Apr 15;2020:7605160. doi: 10.1155/2020/7605160

Figure 2.

Figure 2

NaB shows protective effect on Aβ-induced N2a cell viability decrease. (a) Effect of Aβ25-35 on N2a cell viability. Cells were incubated with 0, 40, 60, or 80 μM Aβ25-35 for 24 hours (n = 4, means ± SD, Student's t-test, ∗∗P < 0.01, and ∗∗∗P < 0.001). (b) Effect of 2 mM NaB pretreatment on cell viability challenged by 40 μM Aβ25-35 for 24 hours. Cells were starved for 4 h and then pretreated with 2 mM NaB for 2 h before Aβ25-35 was added. Cell viability was analyzed by the CCK-8 assay (n = 4, means ± SD, Student's t-test, ∗∗P < 0.01, and ∗∗∗P < 0.001). When the concentration of Aβ is 40 μM, it had caused obvious damage to the N2a cells. After pretreatment with 2 mM NaB, cell viability was restored.