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. 2020 Apr 15;2020:7605160. doi: 10.1155/2020/7605160

Figure 3.

Figure 3

NaB attenuates Aβ toxicity and maintains mitochondrial respiratory function in N2a cells. Effect of 2 mM NaB pretreatment on ROS challenged by 40 μM Aβ25-35 for 24 hours. Cells were starved for 4 h and then pretreated with 2 mM NaB for 2 h before Aβ25-35 was added. The ROS was assessed by a ROS assay kit (n = 4, means ± SD, Student's t-test, ∗P < 0.05, and ∗∗P < 0.01). When the concentration of Aβ is 40 μM, it had led to increased ROS in N2a cells. After pretreatment with 2 mM NaB, ROS was reduced to normal levels.