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. 2020 Mar 25;20(7):1820. doi: 10.3390/s20071820

Figure 3.

Figure 3

Figure 3

(a) The sandwich-type DNA micro-optode response toward the detection of 1 pM cDNA in 0.05 M K-phosphate buffer from pH 4.4 to pH 8.9 at 637 nm (n = 3). (b) The response time curve of the optical DNA biosensor upon sandwich DNA detection of 1 pM cDNA at 637 nm (n = 3). (c) Reversibility of the DNA biosensor after sandwich DNA hybridization treatment with 1 pM cDNA at pH 7.0 for 90 min (R) and regeneration with 0.1 M NaOH solution for 10 min (N) in ambient conditions (n = 3). (d) The long-term stability profile of the optical DNA biosensor for sensing of 1 pM dengue virus DNA for an experimental time period of seven days (n = 3).