Table 2.

The matrix effect (ME%) and relative matrix effect (RSD% of slopes) evaluated under different sample preparation and evaluation conditions. ME% < 0 means ion suppression, and ME% > 0 means ion enhancement.

	TEA	ALT	AOH	TEN	AME
	Preparation without SPE clean-up and evaluation without ISTD correction
ME% (sample 1)	8	−7	−20	4	−75
ME% (sample 2)	−3	−3	−40	−13	−86
ME% (sample 3)	−5	−18	−48	−14	−88
Relative ME%	7	9	22	11	42
	Preparation without SPE clean-up and evaluation with ISTD correction
ME% (sample 1)	11	−4	11	10	−6
ME% (sample 2)	4	−6	10	0	−11
ME% (sample 3)	5	−19	31	2	5
Relative ME%	4	9	10	5	5
	Preparation with mixed-mode SPE clean-up and evaluation without ISTD correction
ME% (sample 1)	2	10	−45	10	−57
ME% (sample 2)	−10	−8	−57	−15	−50
ME% (sample 3)	−13	3	−46	−18	−62
Relative ME%	9	11	14	17	14
	Preparation with mixed-mode SPE clean-up and evaluation with ISTD correction
ME% (sample 1)	8	1	2	9	6
ME% (sample 2)	−6	−7	4	−12	−3
ME% (sample 3)	−6	3	−18	−4	−8
Relative ME%	8	5	13	11	7