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. 2020 Apr 3;20(7):2017. doi: 10.3390/s20072017

Table 2.

Comparison of other methods for microRNAs detection.

Methods LOD Linear Range Correlation Coefficient (R2) Reference
DNA self-assembled molecular tweezers 0.6 pM 1–500 nM 0.9929 [25]
Graphene oxide for rapid microRNA detection / 50–400 nM 0.9562 [26]
Fluorescence quenching of graphene oxide integrating 3.0fM 0.02–100 pM / [27]
A novel DNA nanomachine based on the linear rolling circle amplification strategy 87fM 0.1 pM–0.1 nM 0.9908 [13]
Highly sensitive determination of microRNA using target-primed and branched rolling-circle amplification 0.25pM 0.025 pM–2.5 nM 0.9994 [23]
Fluorometric determination of microRNA based on strand displacement amplification and rolling circle amplification 1.04fM 10 fM–0.1 nM 0.9957 [19]
Cascade amplification by catalytic DNAzymes 10pM 10 pM–100 nM / [28]
Fluorescence quenching of gold nanoparticles with a competitive hybridization 33.4fM 100 fM–1.0 nM / [29]
DNAzyme-based target-triggered rolling-circle amplification 0.49pM 0–25 pM 0.99106 This work