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. 2020 Apr 17;10:505. doi: 10.3389/fonc.2020.00505

Figure 1.

Figure 1

Plasma HPV-DNA levels at baseline and 12 weeks post-CRT. 14/15 patients had above threshold levels of cHPV-DNA at baseline. At 12 weeks post- CRT, cHPV-DNA levels dropped to below threshold in all 14 patients. (A) 11 patients had complete response on DRE/MRI and cHPV-DNA below threshold. (B) 4 patients with partial response on DRE/MRI at 12 weeks and below threshold cHPV-DNA; further DRE/MRI at 6/12 months showed no evidence of relapse The dashed line on the Y-axis denotes the panHPV-detect threshold at 5.5 amplicons with more than 10 reads.