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. 2020 Apr 17;10:505. doi: 10.3389/fonc.2020.00505

Table 1.

ROC analyses thresholds and results.

Cut-off (no. of amplicons) Sensitivity% 95% CI Specificity% 95% CI Likelihood ratio
>0.5000 100.0 81.5–100.0% 70 47–87% 3.29
>1.5 100.0 81.5–100.0% 74 52–90% 3.83
>2.5 100.0 81.5–100.0% 78 56–93% 4.6
>4 100.0 81.5–100.0% 91 72–99% 11.5
>5.5 100.0 81.5–100.0% 96 78–99.9% 23
>16.5 100.0 81.5–100.0% 100.0 81.5–100.0%
>30.5 95 74–99% 100.0 81.5–100.0%
>37 89 65–98% 100.0 81.5–100.0%
>50.5 84 59–96% 100.0 81.5–100.0%
>62 78 52–93% 100.0 81.5–100.0%
>68 72 47–90% 100.0 81.5–100.0%
>73.5 67 41–87% 100.0 81.5–100.0%
>74.5 61 36–83% 100.0 81.5–100.0%
>76 50 26–74% 100.0 81.5–100.0%
>77.5 28 10–53% 100.0 81.5–100.0%

CI, confidence interval. The bold values stand for the threshold identified for classifying samples into HPV +ve and -ve using the ROC analysis.