Table 1.
Cut-off (no. of amplicons) | Sensitivity% | 95% CI | Specificity% | 95% CI | Likelihood ratio |
---|---|---|---|---|---|
>0.5000 | 100.0 | 81.5–100.0% | 70 | 47–87% | 3.29 |
>1.5 | 100.0 | 81.5–100.0% | 74 | 52–90% | 3.83 |
>2.5 | 100.0 | 81.5–100.0% | 78 | 56–93% | 4.6 |
>4 | 100.0 | 81.5–100.0% | 91 | 72–99% | 11.5 |
>5.5 | 100.0 | 81.5–100.0% | 96 | 78–99.9% | 23 |
>16.5 | 100.0 | 81.5–100.0% | 100.0 | 81.5–100.0% | |
>30.5 | 95 | 74–99% | 100.0 | 81.5–100.0% | |
>37 | 89 | 65–98% | 100.0 | 81.5–100.0% | |
>50.5 | 84 | 59–96% | 100.0 | 81.5–100.0% | |
>62 | 78 | 52–93% | 100.0 | 81.5–100.0% | |
>68 | 72 | 47–90% | 100.0 | 81.5–100.0% | |
>73.5 | 67 | 41–87% | 100.0 | 81.5–100.0% | |
>74.5 | 61 | 36–83% | 100.0 | 81.5–100.0% | |
>76 | 50 | 26–74% | 100.0 | 81.5–100.0% | |
>77.5 | 28 | 10–53% | 100.0 | 81.5–100.0% |
CI, confidence interval. The bold values stand for the threshold identified for classifying samples into HPV +ve and -ve using the ROC analysis.