Table 3.
Percentage inhibition of virulence factors of A. baumannii isolates in presence of QSIs
Virulence factor | Azithromycin | Erythromycin | Levamisole | Chloroquine | Propranolol | |
---|---|---|---|---|---|---|
Biofilm | % inhibition range | 33.6–93.3 | 20.2–93.3 | 33.8–92.9 | 67.4–93.5 | 37.8–92.9 |
% of isolates with ≥ 50% inhibition | 80% | 95% | 85% | 100% | 75% | |
Twitching motility | % inhibition range | 7.7–75 | 19.3–81.8 | 11.7–89.5 | 8.3–77.3 | 16.7–80 |
% of isolates with ≥ 50% inhibition | 30% | 30% | 50% | 40% | 35% | |
Surface-associated motility | % inhibition range | 7.7–40 | 7.7–40 | 7.7–40 | 6.7–40 | 6.7–40 |
% of isolates with ≥ 50% inhibition | 60% | 70% | 50% | 20% | 30% | |
Esterase production | % inhibition range | 5–56.5 | 21.9–66.7 | 5.5–59.2 | 5.5–59.2 | 13.4–38.1 |
% of isolates with ≥ 50% inhibition | 10.5% | 31.5% | 5% | 10.5% | 0% | |
Sensitivity to H2O2 | % inhibition range | 6.3–50 | 10–100 | 3.3–100 | 6.7–50 | 6.3–40 |
% of isolates with ≥ 50% inhibition | 5% | 25% | 10% | 15% | 0% | |
Phospholipase production | % inhibition range | 18.2–100 | 13–100 | 26.1–100 | 13–100 | 21.7–100 |
% of isolates with ≥ 50% inhibition | 62.5% | 37.5% | 62.5% | 50% | 62.5% |