Figure 10.
(a) Solubilization of PTX in a polymeric micelle made of amphiphilic block copolymers (Physical loading of anticancer drug into the micelles). Adapted with permission from [63]; copyright (2007) American Chemical Society. (b) Inner structure of micelles with encapsulated Epirubicin covalently linked to the polyaspartate chain of PEG-polyaspartate block copolymer by an acid-labile hydrazone bond. The amphiphilic block copolymers (PEG and polyaspartate) forms spontaneously micellar structures in an aqueous media.
