Table 2.
Different NCs used in cancer therapy, the loaded anticancer agent and their applications in cancer therapy.
| Type of Nanostructure | Anticancer Agent | Applications in Cancer Therapy | Reference |
|---|---|---|---|
| F3O4 nanoparticles | DOX | Controlled drug delivery system/Magnetic carrier | [37] |
| Hollow MSNs | DOX | Controlled drug delivery system under the application of an external stimuli (pH) | [41] |
| (PGLSA)-COONa) dendrimer | 10HCPT | Controlled drug delivery system of hydrophobic drugs | [48] |
| Dendritic phthalocyanine systems | Zinc phthalocyanine | Controlled drug delivery system by photochemical activation | [52] |
| PAMAM dendrimer coated with Hyaluronic acid | Pt and DOX | Controlled drug delivery system under the application of an external stimuli (pH) | [54] |
| Gliadin and Gliadin-gelatin nanoparticles | Cyclophosphamide | Controlled release of anticancer drug in breast cancer cells | [57] |
| Silk nanoparticles | DOX | Controlled drug delivery system under the application of an external stimuli (pH) | [58] |
| PEG-Polyaspartate micelle | Epirubicin | Controlled drug delivery system under the application of an external stimuli (pH) | [62] |
| PEG-b-PLA micelle | PTX | Controlled drug delivery system of hydrophobic drugs | [63] |
| Liposome | DOX | Controlled drug delivery system of toxic drugs | [73] |
| Liposome | CUR | Controlled drug delivery system | [76] |
| PEG-SWNTs | PTX | Controlled drug delivery system | [85] |
| SWNTs | Pt | Targeted drug delivery system | [87] |
| PEG-SWNTs | DOX | Controlled drug delivery system | [88] |
| Graphene oxide QDs covered with luminescent magnetic nanoplatform | - | Human cancer imaging applications | [92] |
| Tripeptide-tagged (arginine-glycine-aspartic) CdTe/ZnS QDs | - | Targeted near-infrared imaging of tumors Cancer detection and management including imaging-guided surgery |
[95] |
| ZnO QDs | DOX | Controlled drug delivery system under the application of an external stimuli (pH) | [99] |
| β-cyclodextrin attached to cellulose nanocrystals | CUR | Targeted and controlled drug delivery system | [104] |
| Chitosan-gellan gum | Tamoxifen citrate | Controlled drug delivery system | [105] |
| Chitosan-poly(N-vinylpyrrolidone-alt-itaconic anhydride) | 5-FU | Controlled drug delivery system under the application of an external stimuli (pH) | [106] |