Table 2.
No Coating | KOS-only | PXL-only | KTO-PXL | p Value | |
---|---|---|---|---|---|
Morphometric Measurements | |||||
EEL, mm2 | 1.87 ± 0.33 | 1.64 ± 0.63 | 1.98 ± 0.48 | 1.39 ± 0.39 | 0.37 |
IEL, mm2 | 1.32 ± 0.24 | 1.15 ± 0.55 | 1.58 ± 0.24 | 0.99 ± 0.45 | 0.52 |
Lumen, mm2 | 1.18 ± 0.24 | 1.00 ± 0.55 | 1.32 ± 0.30 | 0.92 ± 0.43 | 0.58 |
Media, mm2 | 0.55 ± 0.10 | 0.50 ± 0.11 | 0.59 ± 0.18 | 0.40 ± 0.08 | 0.21 |
Neointimal area, mm2 | 0.15 ± 0.06 | 0.14 ± 0.04 | 0.11 ± 0.05 | 0.06 ± 0.02 | 0.085 |
Neointimal thickness, mm | 0.10 ± 0.011 | 0.069 ± 0.022 | 0.066 ± 0.018 | 0.053 ± 0.003 | 0.005 |
Percent area stenosis, % | 10.88 ± 4.52 | 9.99 ± 3.78 | 7.92 ± 3.84 | 6.80 ± 2.74 | 0.45 |
Histological Analysis | |||||
Injury | 1.00 ± 0.41 | 0.75 ± 1.19 | 1.13 ± 1.32 | 0.50 ± 0.41 | 0.74 |
EC Score | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 1.50 ± 0.58 | 0.013 |
Inflammation | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.86 |
SMC Loss | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.25 ± 0.50 | 1.00 ± 0.82 | 0.081 |
Abbreviations: EEL—external elastic lamina, IEL—internal elastic lamina, EC—endothelial cell, SMC—smooth muscle cell.