Scheme 2.
Preparation of [18F]AlF-NOTA-PODS-ZEGFR:03115 and [18F]AlF-NODAGA-PODS-ZEGFR:03115. Reaction conditions: (a) TCEP-HCl, 1 M phosphate buffer pH 7; (b) AlCl3 in sodium acetate pH 4, [18F]F- aq./ethanol 1:1 (v/v), for 15 min, and at 100 °C.
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