Table 2.
Antifungal activity of compounds 1–9.
Compound | Growth Inhibition (%, mean ± SD) * |
MIC (µg mL−1) | ||
---|---|---|---|---|
C. albicans | C. parapsilosis | C. albicans | C. parapsilosis | |
1 | 83.4 ± 3.3 | 81.3 ± 2.6 | 0.21 ± 0.04 | 0.25 ± 0.05 |
2 | 79.8 ± 5.3 | 76.5 ± 4.5 | 0.26 ± 0.07 | 0.31 ± 0.02 |
3 | 85.0 ± 3.4 | 80.0 ± 2.7 | 0.38 ± 0.03 | 0.34 ± 0.06 |
4 | 61.2 ± 3.3 | 69.5 ± 2.4 | 0.89 ± 0.02 | 0.61 ± 0.08 |
5 | 23.6 ± 5.2 | 18.9 ± 3.7 | 0.68 ± 0.01 | 0.79 ± 0.03 |
6 | 19.5 ± 2.9 | 21.7 ± 3.4 | 0.73 ± 0.08 | 0.86 ± 0.07 |
7 | 15.8 ± 3.2 | 10.9 ± 4.7 | 0.97 ± 0.12 | 0.79 ± 0.06 |
8 | 42.7 ± 4.4 | 51.8 ± 2.5 | 0.74 ± 0.05 | 0.62 ± 0.03 |
9 | 45.3 ± 3.7 | 49.9 ± 4.8 | 0.68 ± 0.08 | 0.74 ± 0.02 |
Itraconazole | 54.7 ± 2.6 | 51.5 ± 4.1 | 0.29 ± 0.06 | 0.33 ± 0.04 |
* Results expressed as mean ± standard deviation (SD).