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Cortex-to-cerebellum (a) and hippocampus-to-cerebellum (b) radioactivity ratio at 25 min after injection of [11C]PiB into wild-type and APP/PS1-21 mice aged 170 days (ns, not significant, *p < 0.05, two-sided unpaired t-test). Please refer to Table 1 for number of animals in each group.
