Impact of acute hyperglycaemia on cortical collateral blood flow. (a)
Cortical blood flow map of a representative rat per group. (b)
Cortical blood flow in the ipsilateral ischaemic core ROI. (c) Area
the under curve for cortical perfusion (0.5–4 h) in the ipsilateral
ischaemic core ROI of vehicle and glucose groups,
p > 0.05*. (d) Cortical blood flow in the
ipsilateral hypoperfused ROI. (e) Area under the curve of cortical
perfusion (0.5–4 h) in the ipsilateral hypoperfused ROI. (f)
Cortical perfusion in the ROI contralateral to ischaemic core. (g)
Area under the curve of cortical perfusion in the ROI contralateral
to ischaemic core, p > 0.05*. (h) Cortical
perfusion in the ROI contralateral to the hypoperfused ROI. (i) Area
under the curve of cortical perfusion in the ROI contralateral to
the hypoperfused ROI, p > 0.05*. (j) MABP was
stable during ischaemia, in vehicle and glucose groups. (k) Blood
glucose concentration 10 min prior to and during ischaemia. Data
were analysed using repeated measures two-way ANOVA,
p = 0.0001*. Area under the curve data for
cortical perfusion presented as mean ± SD, other data presented as
mean + SD.