Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 1;25(7):1622. doi: 10.3390/molecules25071622

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Superimposition of the pose of ketoconazole docked in (a) PDB id 1TQN and (b) PDB id 2V0M by IFD over crystal structure of ketoconazole bound CYP3A4 (PDB id 2V0M). The pink dotted line indicates the distance between site of metabolism (SOM) and the Fe atom of heme.

Superimposition of the pose of ketoconazole docked in (a) PDB id 1TQN and (b) PDB id 2V0M by IFD over crystal structure of ketoconazole bound CYP3A4 (PDB id 2V0M). The pink dotted line indicates the distance between site of metabolism (SOM) and the Fe atom of heme.