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(A) Histone 3 acetylation and γ-H2AX level in RT112 cells treated with 5 Gy ionizing radiation either in combination with romidepsin or alone. (B) I-Sce1 assay for romidepsin (n = 3) and (C) nonhomologous end joining assay for romidepsin (n = 2). All error bars represent ± standard error of the mean. *P < .05; ***P < .001; ****P < .0001.
