MCF-7 BUS cell proliferation, after DCE treatment in the presence and absence of 17β-estradiol (E2, 10−9 M). MCF-7 BUS cells were treated with DCE at concentrations 5.0 and 25 μg·mL−1 for 144 h. *, # p < 0.05 and ***, ### p < 0.001 (analysis of variance (ANOVA)). * Statistical difference compared to control of cells without estradiol. # Statistical difference compared to control of cells with estradiol. Results expressed as mean ± standard deviation. Statistical analysis by One-way ANOVA followed by Tukey’s Test *, # p < 0.05 and ***, ### p < 0.001 (ANOVA). * Statistical difference in relation to control of cells without estradiol. # statistical difference compared to cells controlled with estradiol.