Survival of mice re-inoculated with ID8-ip1-Luc ovarian cancer cells after combined photothermolysis and immunotherapy. (A) Experimental design diagram. (B) Kaplan-Meyer survival curves. Combination treatment (8 OD CuS NPs + PW laser 1 min + PG-CpG + αPD-1 groups) compared to photothermolysis alone, immunotherapy alone, and untreated control group (n = 10/group). **p<0.01, log-rank Mantel-Cox test. i.p., intraperitoneal; i.t., intratumoral; i.v., intravenous; s.c., subcutaneous.