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Comparison of peficitinib Cmax and AUC12 between days 1 and 7
| Parameter (day 7/day 1) | Dose | GMR | 90% CI |
|---|---|---|---|
| Cmax | 10 mg bid | 1.28 | 1.03, 1.58 |
| 30 mg bid | 1.13 | 0.90, 1.44 | |
| 100 mg bid | 1.25 | 1.10, 1.42 | |
| AUC12 | 10 mg bid | 1.28 | 1.02, 1.62 |
| 30 mg bid | 1.25 | 1.04, 1.51 | |
| 100 mg bid | 1.37 | 1.19, 1.57 |
AUC12 area under the plasma concentration–time curve from the time of dosing to 12 h post-dose, bid twice daily, CI confidence interval, Cmax maximum plasma concentration, GMR geometric mean ratio
