Table 6.

Multivariate analysis of recurrence-free survival and overall survival

Varient	DFS		OS
	HR (95% CI)	P	HR (95% CI)	P
Age (years)	1.901 (0.465–7.774)	0.371	1.881 (0.327–10.820)	0.479
Tumor size (cm)	0.915 (0.242–3.452)	0.895	0.459 (0.104–2.026)	0.304
Histological grade	NA	0.135	NA	0.134
Lymphnode metastasis	0.223 (0.060–0.827)	0.025	0.088 (0.017–0.470)	0.004
Stage	0.621 (0.149–2.590)	0.513	0.401 (0.073–2.191)	0.291
Depth of stromal invasion	0.885 (0.272–2.885)	0.840	2.274 (0.529–9.785)	0.270
Treatment	0.385 (0.106–1.407)	0.149	0.248 (0.045–1.360)	0.108
Respond of neoadjuvant therapy	3.662 (0.754–17.784)	0.107	5.299(0.767–36.612)	0.091

DFS disease free survival, OS overall survival, CI confidence interval, HR hazard radio, NA not available