Table 3.

Cox proportional hazard model of the association between total sugar consumption and all-cause mortality

	Number	Deaths, no.	First quintile, 0.4–81.9 g, n = 39,660, HR (95% CI)	Second quintile, 82–105 g, n = 39,655, HR (95% CI)	Third quintile, 106–126 g, n = 39,663, HR (95% CI)	Fourth quintile, 127–154 g, n = 39,650, HR (95% CI)	Highest quintile, 155–1051 g, n = 39,657, HR (95% CI)	p value for trend
Deaths, no.			632	615	599	599	723
Model
0	198,283	3166	1 (Ref)	0.96 (0.86–1.08)	0.94 (0.84–1.05)	0.94 (0.84–1.05)	1.15 (1.03–1.27)	0.034
1	197,590	3150	1 (Ref)	0.90 (0.81–1.01)	0.84 (0.75–0.94)	0.81 (0.73–0.91)	0.95 (0.86–1.06)	0.156
2	161,415	2311	1 (Ref)	1.02 (0.97–1.27)	0.98 (0.87–1.15)	1.00 (0.94–1.25)	1.19 (0.95–1.30)	0.108
3	161,415	2311	1 (Ref)	1.04 (0.91–1.19)	0.99 (0.87–1.15)	1.03 (0.88–1.20)	1.25 (1.04–1.50)	0.076
4	161,415	2311	1 (Ref)	1.05 (0.92–1.20)	1.02 (0.88–1.18)	1.05 (0.90–1.23)	1.28 (1.06–1.55)	0.057

Model 0: unadjusted

Model 1: adjusted for sex, age and ethnicity

Model 2: model 1 also adjusted for income, highest qualification, physical activity, sedentary behaviour, total energy intake, body mass index, smoking status and alcohol intake

Model 3: model 2 also adjusted for total fat intake

Model 4: model 3 also adjusted for fresh fruit intake, vegetable intake, total fibre intake, red meat intake and processed meat intake

Median total sugar intake: 1st quintile, 68 g; 2nd quintile, 94 g; 3rd quintile, 115 g; 4th quintile, 139 g; 5th quintile, 179 g

N number, HR hazard ratio, CI confidence interval