Table 5.
Hazard ratios of all-cause mortality according to KDPI score and the age of KTRs.
| Unadjusted HR (95% C.I.) | P | Adjusted HRa (95% C.I.) | P | P-value for interaction | |
|---|---|---|---|---|---|
| Low KDPI-young KTR | Reference | Reference | 0.420 | ||
| Low KDPI-elderly KTR | 4.177 (1.304–13.379) | 0.016 | 2.841 (0.314–25.737) | 0.353 | |
| High KDPI-young KTR | 2.013 (0.918–4.416) | 0.081 | 1.590 (0.509–4.962) | 0.425 | |
| High KDPI-elderly KTR | 2.386 (0.809–7.036) | 0.115 | 2.870 (0.636–12.961) | 0.170 |
aAdjusted by DGF, transplant years (1996~2005 vs. 2006~2010 vs. 2011~2017), prior KT, DM of KTRs, HLA mismatch number, high PRA (>50%), eGFR calculated by CKD-EPI equation at 12 months after KT, sex, age of donor, acute rejection, malignancy.
Abbreviations: KDPI, kidney donor profile index; KTR, kidney transplant recipient; HR, hazard ratio; DGF, delayed graft function; KT, kidney transplantation; DM, diabetes mellitus; HLA, human leukocyte antigen; PRA, panel reactive antibody; eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration.