Fig. 2. MiR-4476 promotes xenograft tumor growth in vivo.
a Images of xenograft tumor models of mice injected with U87 cells transfected with miR-4476 lentiviral expression particles or negative control (NC) lentiviral expression particles. b Tumor volume was periodically measured for each mouse and tumor growth curves were plotted. c Tumor weight was measured at the 21st day after inoculation in each group. d IHC staining was used to detect and quantify Ki-67 expression in xenograft tumors from mice injected with U87 cells; scale bar = 75 μm. Mean ± S.D., *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.