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. 2020 Apr 24;10:6921. doi: 10.1038/s41598-020-63906-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Trade-off line graph according to various cut-off probabilities calculated by XGB model. The x-axis indicates probability values calculated from the model. The scale of the solid line is shown on the left axis, and the scale of the dotted line is shown on the right axis. The red vertical line indicates the optimal cut-off value maximizing sensitivity + specificity. (A) Trends of the number of predictions. The y-axis represents the number of subjects. (B) Trends of performance indicators. The y-axis represents the performance scores.