Table 1.
Correlation of clinico-pathological features with DDX11 expression in ZZU HCC TMA cohort.
| Variables | Clinicopathological features | DDX11 expression | P value | |
|---|---|---|---|---|
| Low expression (n = 165) | High expression (n = 170) | |||
| Age (years) | ≤53 | 88(53.3) | 94(55.3) | 0.718 |
| >53 | 77(46.7) | 76(44.7) | ||
| Gender | Male | 121(73.3) | 115(67.6) | 0.254 |
| Female | 44(26.7) | 55(32.4) | ||
| Pathogenesis | Virus | 124(75.2) | 131(77.1) | 0.407 |
| Alcohol | 25(15.2) | 29(17.1) | ||
| Others | 16(9.7) | 10(5.9) | ||
| Cirrhosis | Absent | 22(13.3) | 34(20.0) | 0.102 |
| Present | 143(86.7) | 136(80.0) | ||
| Vascular invasion | Absent | 97(66.7) | 119(62.4) | 0.032 |
| Present | 68(33.3) | 51(37.6) | ||
| TNM stage | Stage I and II | 112(67.9) | 96(56.5) | 0.031 |
| Stage III and IV | 53(32.1) | 74(43.5) | ||
| Tumor size(cm) | ≤5 | 108(65.5) | 82(48.2) | 0.001 |
| >5 | 57(34.5) | 88(51.8) | ||
| Lymph metastasis | No | 97(58.9) | 91(53.5) | 0.332 |
| Yes | 68(41.2) | 79(46.5) | ||
| AFP | ≤ 20 | 83(50.3) | 80(47.1) | 0.552 |
| >20 | 82(49.7) | 90(52.9) | ||
| Child-Pugh | A | 19(11.5) | 27(15.9) | 0.777 |
| B | 76(46.1) | 80(47.1) | ||
| C | 70(42.4) | 63(37.1) | ||
| Tumor multiplicity | Single | 75(45.5) | 81(47.6) | 0.687 |
| Multiple | 90(54.5) | 89(52.4) | ||
| DDX11 expression | Live | 122(73.9) | 105(61.7) | 0.017 |
| Dead | 43(26.1) | 65(38.2) | ||
Bold values indicate statistical significance, P < 0.05.