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. 2020 Apr 17;11:286. doi: 10.3389/fphys.2020.00286

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Copyright © 2020 Kumkhong, Marandel, Plagnes-Juan, Veron, Boonanuntanasarn and Panserat.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of the glucose injection history and dietary carbohydrate challenge on the global DNA methylation in Nile tilapia. The levels of 5-methylcytosine (5-mC%: 5-mC/total DNA) in the DNA in the liver (A) and muscles (B) were measured in fish challenged with different dietary carbohydrate levels (37% carbohydrates, CHO-M; 67% carbohydrates, CHO-H). Data are presented as the mean ± SD (n = 6). Two-way ANOVA was used to analyze the effects of glucose injection (History), challenging diet (Diet) and their interaction (History × Diet).