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. 2020 Apr 24;4:9. doi: 10.1038/s41698-020-0116-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Graph depicts quantitation Gas6 protein staining of TMAs, expressed as the percentage (%) of patients expressing epithelial Gas6 protein in different molecular subtypes: normal breast (n = 9), luminal A (n = 39), luminal B (n = 18), Her2⁺ (n = 19), and TNBC (n = 19). b Mean Gas6 mRNA expression across distinct molecular subtypes relative to non-cancer and normal-like breast tissues, using METABRIC dataset (non-cancerous, n = 6; normal-like cancers, n = 140; luminal A, n = 679; luminal B, n = 461; Her2, n = 219; basal-like, n = 198; claudin low, n = 199). c Mean Gas6 mRNA expression across distinct molecular subtypes relative to normal-like breast tissues, using TCGA data set (normal-like cancers, n = 8; luminal A, n = 212; luminal B, n = 119; Her2, n = 55; basal-like, n = 87). Middle line is median, box borders are 25th to 75th percentiles and bars are minimum and maximum values. Significant p values are depicted in graphs b–c from one-way ANOVA followed by post hoc Dunnett’s multiple comparison test. ns not significant.