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. 2020 Apr 24;11:2011. doi: 10.1038/s41467-020-15639-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The y-axis depicts the SMR with 95% CI, and the x-axis depicts the disease site. Different time periods after diagnosis (<1 year vs 1–5 years vs 5–10 years vs >10 years) are shown in blue, orange, grey, and yellow, respectively. At the 1–5 year post-diagnosis time point, the risk of heart disease among cancer patients is two times that of the general population and rises with longer follow-up time. Certain cancer patients have relatively high SMR from heart disease in the first year after diagnosis (e.g. lung with SMR of 13.3, and myeloma with SMR of 7.5). These 12 cancer were chosen as they represent the sites with the greatest number of person–years at risk. Total person years at risk = 1,195,381.08. Error bars represent the 95% CI by site. Source data are provided as a Source Data file.