Table 1. Blastomycosis patient demographics and health-related data, by outcome, Minnesota, USA, 1999–2018*.
| Category | All patients, n = 671 | Patients with nonfatal cases, n = 602 | Patients with fatal cases, n = 64 | OR (95% CI)† | p value† |
|---|---|---|---|---|---|
| Mean age ± SD, y |
44 ± 19.2 |
42 ± 18.5 |
57 ± 20.7 |
|
p<0.001‡ |
| Sex | NS | ||||
| M | 474 (71) | 426 (71) | 45 (70) | ||
| F |
197 (29) |
176 (29) |
19 (30) |
|
|
| Race | NS | ||||
| White | 490 (83) | 446 (84) | 44 (75) | ||
| American Indian/Alaska Native | 40 (7) | 32 (6) | 7 (12) | ||
| Black | 31 (5) | 27 (5) | 3 (5) | ||
| Asian/Pacific Islander | 23 (4) | 19 (4) | 4 (7) | ||
| Other/Mixed race |
4 (1) |
4 (1) |
0 |
|
|
| Ethnicity | NS | ||||
| Non-Hispanic | 439 (96) | 398 (96) | 41 (95) | ||
| Hispanic |
18 (4) |
16 (4) |
2 (5) |
|
|
| Location of disease | NS | ||||
| Pulmonary only | 469 (72) | 425 (72) | 43 (69) | ||
| Disseminated | 137 (21) | 117 (20) | 19 (31) | ||
| Nonpulmonary |
46 (7) |
46 (8) |
0 |
|
|
| Concurrent conditions | |||||
| Any | 195 (35) | 157 (30) | 36 (71) | 5.3 (2.7–10.5) | p<0.001 |
| Chronic illnesses | 109 (22) | 87 (19) | 20 (57) | 5.5 (2.6–11.6) | p<0.001 |
| Diabetes mellitus | 81 (17) | 68 (16) | 11 (42) | 3.6 (1.5–8.7) | p = 0.005 |
| Chronic lung disease | 15 (4) | 11 (3) | 4 (21) | 10.2 (2.7–38.6) | p<0.001 |
| Immunocompromise | 46 (11) | 34 (8) | 12 (44) | 8.6 (3.4–21.8) | p<0.001 |
| Steroid use | 15 (4) | 8 (2) | 7 (32) | 21.1 (6.3–70.8) | p<0.001 |
| Rheumatoid arthritis treatment | 13 (3) | 9 (2) | 4 (21) | 10.6 (2.3–48.8) | p = 0.002 |
| Cancer | 24 (6) | 19 (5) | 5 (25) | 7.7 (2.4–25.5) | p<0.001 |
*Values are no. (%) except as indicated. Denominators may not be same across categories because not all data were available for all patients. OR, odds ratio; NS, not significant. †ORs and p values calculated by using univariable logistic regression, except for concurrent conditions analyses, which were controlled for race and sex. ‡p value calculated by using Student t test.