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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Arch Pharm Res. 2019 Nov 28;43(3):337–349. doi: 10.1007/s12272-019-01192-3

Figure 1: Hepatic shunt in Nrf2 KO mice.

Figure 1:

Altered acetaminophen toxicity and portal vasculature in wild-type versus Nrf2 KO C57BL/6J mice. Top. Plasma alanine aminotransferase (ALT) levels in 10-week old fasted wild-type and Nrf2 KO mice following acetaminophen challenge (250 mg/kg, i.p) after 6 hours. Means ± SE. Bottom. Micro computed tomography of livers perfused through the portal vein with radio-opaque Microfil in Nrf2 KO mice with intrahepatic shunt and wild-type mice. Figure adapted from Skoko et al. (2014).