. 2018 Jul 18;68(6):976–983. doi: 10.1093/cid/ciy580

Table 2.

Monthly All-cause Acute Gastroenteritis Hospitalization Rates and Adjusted RRs, Restricted to the Rotavirus Season: Prevaccine Period Compared With Postvaccine Period by Year^a

Age Group, y	2008		2009		2010		2011		2012		2013
Age Group, y	Rate^b	RR^c (95% CI)	Rate^b	RR^c (95% CI)	Rate^b	RR^c (95% CI)	Rate^b	RR^c (95% CI)	Rate^b	RR^c (95% CI)	Rate^b	RR^c (95% CI)
0–4	5.08	0.66 (.43–1.01)	5.67	0.74 (.46–1.18)	3.70	0.49 (.29–.81)^d	4.08	0.54 (.3–.94)^d	2.97	0.40 (.22–.72)^d	3.66	0.49 (.26–.94)^d
5–19	0.71	0.81 (.65–.99)^d	0.84	0.93 (.74–1.17)	0.80	0.86 (.67–1.11)	0.83	0.88 (.67–1.16)	0.74	0.76 (.57–1.03)	0.83	0.84 (.61–1.16)
20–59	2.26	0.95 (.77–1.19)	2.67	1.05 (.83–1.34)	2.66	0.98 (.76–1.28)	2.68	0.93 (.69–1.23)	2.73	0.88 (.65–1.20)	2.71	0.82 (.58–1.15)
≥60	14.55	0.94 (.68–1.32)	16.87	1.00 (.70–1.44)	15.82	0.86 (.58–1.28)	16.18	0.81 (.52–1.25)	15.60	0.72 (.45–1.14)	15.43	0.65 (.39–1.08)

Abbreviations: CI, confidence interval; RR, rate ratio.

^aData from 26 US states from the Healthcare Cost and Utilization Project’s State Inpatient Databases; see Data Sources, in Methods, for the full list of states. Adjusted RRs are from negative binomial regression comparing the prevaccine period (2000–2006) with postvaccine period (2008–2013) by year, controlling for time and restricted to the rotavirus season (January–June).

^bUnadjusted rate per 10000 age-specific population.

^cRR for comparison with prevaccine era.

^dSignificant at the α = .05 level.