Database	Period of Search	Search Strategy
The Cochrane Hepato‐Biliary Group Controlled Trials Register	Issue 4, 2008	(((ischaemia OR ischaemia OR ischemic OR ischaemic OR reperfusion) AND (injury OR injuries OR damage OR damages)) OR gabexate mesilate OR steroid OR steroids OR corticosteroid OR corticosteroids OR glucocorticoid OR glucocorticoids OR allopurinol OR prostaglandin OR prostaglandins OR amrinone OR dopexamine OR antioxidant OR antioxidants OR prostanoid OR prostanoids OR thiol OR bucillamine OR n‐acetylcysteine) AND ((liver OR hepatic OR hepato) AND (resection OR segmentectomy) OR hepatectomy)
Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (Wiley)	Issue 4, 2008	#1 (ischaemia OR ischaemia OR ischemic OR ischaemic OR reperfusion) AND (injury OR injuries OR damage OR damages) #2 MeSH descriptor Reperfusion Injury explode all trees #3 gabexate mesilate OR steroid OR steroids OR corticosteroid OR corticosteroids OR glucocorticoid OR glucocorticoids OR allopurinol OR prostaglandin OR prostaglandins OR amrinone OR dopexamine OR antioxidant OR antioxidants OR prostanoid OR prostanoids OR thiol OR bucillamine OR n‐acetylcysteine #4 MeSH descriptor Glucocorticoids explode all trees #5 MeSH descriptor Allopurinol explode all trees #6 MeSH descriptor Prostaglandins explode all trees #7 MeSH descriptor Antioxidants explode all trees #8 (#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7) #9 liver OR hepatic OR hepato #10 MeSH descriptor Liver explode all trees #11 (#9 OR #10) #12 resection OR segmentectomy #13 (#11 AND #12) #14 hepatectomy#15MeSH descriptor Hepatectomy explode all trees#16(#13 OR #14 OR #15) #17 (#8 AND #16)
MEDLINE (Pubmed)	January 1951 to January 2009	(((ischaemia OR ischaemia OR ischemic OR ischaemic OR reperfusion) AND (injury OR injuries OR damage OR damages)) OR "Reperfusion Injury"[Mesh] OR (gabexate mesilate OR steroid OR steroids OR corticosteroid OR corticosteroids OR glucocorticoid OR glucocorticoids OR "Glucocorticoids"[Mesh] OR allopurinol OR "Allopurinol"[Mesh] OR prostaglandin OR prostaglandins OR "Prostaglandins"[Mesh] OR amrinone OR dopexamine OR antioxidant OR antioxidants OR "Antioxidants"[Mesh] OR prostanoid OR prostanoids OR thiol OR bucillamine OR n‐acetylcysteine)) AND (((liver OR hepatic OR hepato OR "liver"[MeSH]) AND (resection OR segmentectomy)) OR hepatectomy OR "hepatectomy"[MeSH]) AND (((randomized controlled trial [pt] OR controlled clinical trial [pt] OR randomized controlled trials [mh] OR random allocation [mh] OR double‐blind method [mh] OR single‐blind method [mh] OR clinical trial [pt] OR clinical trials [mh] OR ("clinical trial" [tw]) OR ((singl* [tw] OR doubl* [tw] OR trebl* [tw] OR tripl* [tw]) AND (mask* [tw] OR blind* [tw])) OR (placebos [mh] OR placebo* [tw] OR random* [tw] OR research design [mh:noexp]) NOT (animals [mh] NOT human [mh]))))
EMBASE (OvidSP)	Janurary 1974 to January 2009	1 (ischaemia or ischaemia or ischemic or ischaemic or reperfusion).af.  2 (injury or injuries or damage or damages).af. 3 1 and 2 4 exp Reperfusion Injury/ 5 (gabexate mesilate or steroid or steroids or corticosteroid or corticosteroids or glucocorticoid or glucocorticoids or allopurinol or prostaglandin or prostaglandins or amrinone or dopexamine or antioxidant or antioxidants or prostanoid or prostanoids or thiol or bucillamine or n‐acetylcysteine).af. 6 exp Glucocorticoid/ 7 exp Allopurinol/ 8 exp Prostaglandin E1/ 9 exp Prostaglandin E2/ 10 exp Antioxidant/ 11 6 or 3 or 7 or 9 or 8 or 4 or 10 or 5 12 (liver or hepatic or hepato).af. 13 (resection or segmentectomy).af. 14 13 and 12 15 hepatectomy.af. 16 exp Liver Resection/ 17 16 or 15 or 14 18 11 and 17 19 exp CROSSOVER PROCEDURE/ 20 exp DOUBLE BLIND PROCEDURE/ 21 exp SINGLE BLIND PROCEDURE/ 22 exp RANDOMIZED CONTROLLED TRIAL/ 23 (((RANDOM* or FACTORIAL* or CROSSOVER* or CROSS) and OVER*) or PLACEBO* or (DOUBL* and BLIND*) or (SINGL* and BLIND*) or ASSIGN* or ALLOCAT* or VOLUNTEER*).af. 24 22 or 21 or 23 or 19 or 20 25 18 and 24
Science Citation Index Expanded (http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&Func=Frame)	January 1945 to January 2009	#1 TS=((ischaemia OR ischaemia OR ischemic OR ischaemic OR reperfusion) AND (injury OR injuries OR damage OR damages)) #2 TS=(gabexate mesilate OR steroid OR steroids OR corticosteroid OR corticosteroids OR glucocorticoid OR glucocorticoids OR allopurinol OR prostaglandin OR prostaglandins OR amrinone OR dopexamine OR antioxidant OR antioxidants OR prostanoid OR prostanoids OR thiol OR bucillamine OR n‐acetylcysteine) #3 #2 OR #1 #4 TS=((liver OR hepatic OR hepato) AND (resection OR segmentectomy) OR hepatectomy) #5 TS=(random* OR blind* OR placebo* OR meta‐analysis) #6 #5 AND #4 AND #3