Li 2004.

Methods	Randomised clinical trial.
Participants	Country: China. Number randomised: initially 31, post randomisation drop outs 0, final number of study participants 31. Mean age: 50.2 years. Females: 5 (16.1%). Cirrhotic livers: 27 (87.1%). Steatotic livers: not stated. Inclusion criteria: 1. Elective hepatic resection. 2. Portal triad clamping. 3. Diagnosis of primary hepatocellular carcinoma.
Interventions	Participants were randomly assigned to two groups: Intervention group 1: administered 10000 IU of ulinastatin during the operation, and twice a day with combination of vitamin K1 and glucose for 5 consecutive days after the operation (n = 16). Intervention group 2: administered gantaile (a Chinese herbal medicine used as a 'common liver protectant') the dose for which was not given, vitamin K1, and glucose (n = 15).
Outcomes	The outcomes reported were mortality, liver decompensation, wound infection, intra‐abdominal infection, hospital stay, blood loss, markers of liver function, and enzyme markers of liver injury.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	Quote: "sealed envelope".
Blinding? All outcomes	High risk	Comment: trial not double blinded.
Incomplete outcome data addressed? outcomes 2‐4 weeks	Low risk	Comment: no post randomisation drop‐outs.
Free of selective reporting?	Low risk	Comment: all important outcomes reported.
Free from baseline imbalance?	Low risk	Comment: no baseline imbalance in important characteristics.
Free from academic bias?	Low risk	Comment: no previous published studies of the same comparison by the trial authors.