Fig 1. Volcano plot shows the profile of the differential miRNAs expression in 4 tissue samples of patients with HCC.

The x-axis represents the Log₂ fold change and y-axis represents significance level expressed as the—log₁₀ P-value. The red 3 dots shown in the volcano plot are the downregulated miRNAs in HCC tissue. The blue dots represent miRNAs that did not demonstrate a significant change in expression. Significance value was indicated with a P-value cut-off of 0.05.