Table 3. Variables associated with overall survival in patients with HCC.

Variables	Category	Overall survival
		Univariate analysis		Multivariate analysis
		OR (95%CI)	P	OR (95%CI)	P
Age (years)	< 50 vs. ≥ 50	0.70 (0.33–1.48)	0.347
Gender	Male vs. Female	1.17 (0.51–2.68)	0.709
Aspartate aminotransferase (IU/L)	< 60 vs. ≥ 60	1.44 (0.68–3.05)	0.342
Alanine aminotransferase (IU/L)	< 50 vs. ≥ 50	0.76 (0.36–1.60)	0.465
Platelet count (109/L)	≥ 140 vs. <140	1.81 (0.83–3.95)	0.134
HBeAg positivity	Negative vs. Positive	1.43 (0.65–3.18)	0.376
Log10 HBV DNA (IU/mL)	< 4.0 vs. ≥ 4.0	0.69 (0.29–1.63)	0.393
Child-Pugh classification	A vs. B and C	1.26 (0.58–2.76)	0.560
Alpha fetoprotein (ng/mL)	< 100 vs. ≥ 100	2.76 (1.26–6.07)	0.011*	1.28 (0.55–2.97)	0.571
Tumor size (cm.)	<5.0 vs. ≥ 5.0	4.21 (1.52–11.68)	0.006*	0.99 (0.23–4.22)	0.985
BCLC stage	0-B vs. C, D	5.74 (1.86–17.75)	0.002*	9.27 (1.99–43.14)	0.005*
miR-223-3p	≥ 0.13 vs. < 0.13	4.38 (1.66–11.56)	0.003*	6.61 (2.36–18.55)	<0.001*
miR-199a-5p	≥ 0.46 vs. < 0.46	0.81 (0.38–1.72)	0.589
miR-451a	≥ 0.05 vs. < 0.05	1.03 (0.49–2.18)	0.933