Table 1.
Characteristics of the NLGN4 Gene, cDNA, and Protein in Human and Rodents.
| Species | Gene | cDNA |
Protein |
|||
|---|---|---|---|---|---|---|
| Size (kb) | GC (%) | GC3 (%) | AA | pI | MW (kDa) | |
| Homo sapiens (X chr.) | 259 | 52.9 | 66.5 | 836 | 5.65 | 94.0 |
| Homo sapiens (Y chr.) | 219 | 51.3 | 63.8 | 836 | 5.71 | 94.2 |
| Castor canadensis | >243a | 55.7 | 71.8 | 836 | 5.70 | 94.0 |
| Cavia porcellus | 274 | 55.5 | 74.2 | 836b | 5.77 | 94.1 |
| Chinchilla lanigera | 305 | 54.5 | 71.3 | 836b | 5.70 | 94.0 |
| Cricetulus griseus (E) | 11 | 73.3 | 98.2 | 888c | 6.22 | 95.1 |
| Fukomys darmarensis | 257 | 58.9 | 81.4 | 836b | 5.63 | 93.8 |
| Heterocephalus glaber | 277 | 56.5 | 76.3 | 836b | 5.71 | 93.9 |
| Ictidomys tridecemlineatus | 113 | 62.5 | 91.6 | 837 | 5.75 | 93.8 |
| Mesocricetus auratus (E) | 4.7 | 74.7 | 85.2 | 635c | 10.45 | 65.4 |
| Microtus ochrogaster (E) | 7.5 | 74.0 | 89.3 | 1,043 | 5.73 | 107.0 |
| Mus musculus (E) | 18 | 75.2 | 96.8 | 954 | 5.83 | 98.2 |
| Nannospalax galili | 266 | 52.5 | 65.6 | 836 | 5.82 | 94.1 |
| Octodon degus | 338 | 58.4 | 81.4 | 836b | 5.66 | 93.8 |
| Ondatra zibethicus (E) | 5.2 | 71.7 | 86.9 | 853c | 6.26 | 91.3 |
| Peromyscus maniculatus (E) | 15 | 70.2 | 87.4 | 1,202 | 5.62 | 129.3 |
| Sigmodon hispidus (E) | 9.3 | 71.0 | 94.5 | 876c | 6.14 | 94.0 |
note.—Total gene sizes are rounded to full kb starting from the protein coding ATG to the translational stop codon. GC content, frequency at any position in the cDNA; GC3 content, frequency of either G or C in the third position; AA, number of amino acids in each protein; pI, isoelectric point; MW, calculated molecular weight; E, species member of the clade eumuroidea.
a
Minimal estimated gene size due to a sequencing gap.
b
Alternative ATG might increase amino acid count to 841.
c
Absence of exon 3.