Table 2.
Results of Univariate and Multivariate Cox Regression Comparing the Hazards of Death of Patients With Extracranial Metastases Alone or With Brain Metastases
| HR | 95% CI | P | |
|---|---|---|---|
| Univariate analysis | |||
| Brain metastasis vs extracranial metastases alone | 1.43 | [1.41–1.44] | <.001 |
| Multivariable analysis | |||
| Brain metastasis vs extracranial metastases alone | 1.56 | [1.54–1.58] | <.001 |
| Male vs female sex | 1.13 | [1.12–1.14] | <.001 |
| Year of diagnosis (per each year increase) | 0.98 | [0.98–0.98] | <.001 |
| Age (per each year increase) | 1.02 | [1.02–1.02] | <.001 |
| T-stage | |||
| T0 vs T1 | 1.1 | [1.06–1.14] | <.001 |
| T2 vs T1 | 1.18 | [1.16–1.20] | <.001 |
| T3 vs T1 | 1.12 | [1.10–1.13] | <.001 |
| T4 vs T1 | 1.31 | [1.29–1.33] | <.001 |
| TX vs T1 | 1.51 | [1.48–1.53] | <.001 |
| N-stage | |||
| N+ vs N0 | 1.15 | [1.14–1.17] | <.001 |
| NX vs N0 | 1.18 | [1.17–1.20] | <.001 |
| Race | |||
| American Indian/Alaska Native vs white | 1.05 | [1.00–1.11] | .036 |
| Asian/Pacific Islander vs white | 0.86 | [0.85–0.87] | <.001 |
| Black vs white | 1.08 | [1.06–1.09] | <.001 |
| Unknown vs white | 0.51 | [0.46–0.57] | <.001 |
| Coexisting lung/bone/ liver metastasis vs no lung/bone/liver metastasis | 1.15 | [1.14–1.16] | <.001 |
HR, hazard ratio; CI, confidence interval.