Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Int Forum Allergy Rhinol. 2019 Dec 23;10(4):481–488. doi: 10.1002/alr.22514

Figure 5.

Figure 5.

Characteristics of Ion Transport

A. After 3 weeks of treatment with CISS, the ion transport characteristics were significantly different from those rabbits who had control stents. Sinus PD measurements revealed significantly increased response to Cl− free ringers + forskolin in sinusitis rabbits treated with CISS compared to those that had control stents

CISS: Ciprofloxacin Ivacaftor coated Sinus Stent

B. CISS promoted transepithelial Cl− secretion in a cyclic AMP dependent fashion, indicative of improved CFTR activity (Cl− free + forskolin ΔPD (mV), Control = −4.23 +/− 1.04, CISS = −18.36 +/− 6.31, p = 0.026).

CISS: Ciprofloxacin Ivacaftor coated Sinus Stent