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. 2020 Apr 25;141:109786. doi: 10.1016/j.mehy.2020.109786

Table 1.

Comparison between PCR and LAMP based methods of viral RNA detection. Table adapted from Nguyen et al (2020).

PCR LAMP
Bulky and cumbersome Smaller, simpler, portable.
Specialised thermal cyclers required Only a heat block is required
4–8 h until result 1 h until result
Requires skilled technicians Requires no specific skill
Requires an additional reverse transcription step Can be performed directly on RNA
Unstable reactions prone to inhibitors requiring purification steps Stable and inhibitors tolerated, and thus purification steps not required
Detects DNA Detects DNA and RNA
Tested on patient samples Less tested on patient samples